The hospital building in the "then" photo was newly constructed when the image was shot back in 1907 (southwest corner of Henry Street and South Essex Avenue). Although slated for demolition, the original building was still standing as of 2007. Note the trolley tracks in front of the hospital in the original photo. This route is now assumed by NJ Transit's #92 bus.
The entire hospital complex (more than 9 buildings) is scheduled to be razed in the near future to make way for a mixed-income housing development - given the site's close proximity to Orange Station (with Midtown Direct service to Manhattan) and Interstate 280.